Cyrene & Mydei Team Analysis - Honkai Star Rail 3.7

In Honkai: Star Rail, 5-star Imaginary Destruction character Mydei has gained attention for his unique output mechanism. Auxiliary characters, as the “buff engine”, determine a main DPS’s upper limit. When Mydei pairs with different supports, will it be extreme damage with dispersion/damage-increasing supports, sustained combat with sustain/buff supports, or smooth cycles with energy recharge/coordination supports?

This article will compare Mydei’s effectiveness with different supports and show how to choose the best “support partner” to maximize his combat power.

Mydei Cyrene Team

Mydei’s core damage mechanism lies in his combat skill, which triggers damage by consuming his own health. This health consumption occurs either when his action gauge is charging or when he takes hits.

Cerydra’s greatest enhancement to Mydei is actually optimizing his damage structure—originally, Mydei had almost no control over when to burst damage, but Cerydra’s mechanics allow him to manually adjust the burst timing to adapt to various mechanical challenges.

After understanding Cerydra’s core boost to Mydei, it’s easy to see that Cyrene further optimizes Mydei’s damage mode on this basis: upgrading his original “primitive damage logic” that purely relied on action gauge charging and taking hits to the most valuable “extra-turn ultimate damage” in this game. More importantly, Cyrene’s ultimate trigger depends on the number of teammates’ actions, not Mydei’s own action frequency. In the team system of “Cerydra + Cyrene”, both Cerydra and Cyrene are teammates that can be stacked to extremely high speeds; when Mydei takes 1 action and teammates take 2 actions, Cyrene can release an ultimate (equivalent to “1 layer of Godslayer Be God + Cerydra’s 2 actions + Mydei’s 1 action”, accumulating 3 layers of Military Merit); if there are hits taken during this period that fully charge Cerydra and allow him to release his ultimate, 5 layers of Military Merit can be accumulated, which is enough to support a burst output. In other words, the advantage of teammates’ high-speed actions can be directly converted into Mydei’s damage output through Cyrene’s mechanics.

Mydei Hypercarry Team

In this team, Sunday, as the core support, provides Turn Advance to enable Mydei to enter the damage cycle faster and trigger the “health-for-damage” mechanism frequently, while his Energy Regen ensures the frequency of Mydei’s ultimate skill rotation, allowing Mydei to quickly accumulate charges, maintain the Blood Feud state, and continuously unleash the high-damage “Godslayer Be God” combat skill. Tribbie’s additional DMG boost and All-Type RES PEN directly enhance Mydei’s damage output.

Notably, the All-Type RES PEN allows Mydei’s damage to penetrate enemies’ defenses more efficiently, and Tribbie’s damage increases due to Mydei’s high HP stat, creating a positive cycle where the main DPS’s attributes support the support’s damage, and the support’s damage in turn feeds back to the main DPS’s output. Luocha, with his massive healing capacity, provides a solid survival guarantee for Mydei’s “health-consumption damage” mode. Whether it’s sustained healing in normal situations or burst healing in high-pressure environments, he can ensure Mydei’s HP remains in a safe range, allowing Mydei to unleash damage without hesitation.

This team perfectly combines Mydei’s “health-for-damage” damage logic with the mechanics of his teammates, achieving a high level of smoothness in the damage cycle, depth and breadth of damage, and stability of survival, making it one of the best solutions for Mydei to maximize his strength.

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Mydei+Castorice Team

In this system, Mydei is a damage dealer and can also serve as the main DPS. The mechanical synergy between the characters is highly in-depth: when acting as the main DPS, Mydei’s core "health-for-damage" mechanism still perfectly aligns with Castorice's Ultimate. Every time Mydei consumes his HP, it charges the "Newbud" layers required for Castorice's Ultimate, accelerating the rhythm of its release. Castorice, in turn, provides powerful area damage and team-wide buffs, and Mydei, as the main DPS, not only exerts his own damage advantages but also creates conditions for Castorice's burst through HP consumption.

Tribbie's buffs are a double boon, enhancing both Mydei's damage and penetration to maximize his main DPS potential, while also strengthening Castorice's output capacity, achieving a "one support buffing two damage dealers" coverage that raises the team's overall damage ceiling. Gallagher's "Besotted" debuff is like a "sustain engine" for the team, converting enemies' damage into continuous healing for our side. For Mydei, who relies on HP consumption as the main DPS, this continuous healing effectively offsets the life loss from his output, allowing him to maintain a stable and high-damage rhythm; meanwhile, it also provides survival security for Castorice, enabling him to focus on his damage cycle without worry.

This composition achieves a balance between output and survival through the mechanical synergy of "Main DPS charging a secondary damage dealer + support providing dual buffs + continuous healing for sustain", making it a flexible system where Mydei can take the role of main DPS and adapt to different team setups.

Comparison of Mydei’s Three Teams

From an output perspective, Mydei’s three teams differ sharply in output ceiling, rhythm, and conversion efficiency:

The Cyrene Team leads with the highest output ceiling—Cyrene’s Ultimate stacks up to 5 “Military Merit” layers for Mydei’s exponential burst damage. Its rhythm is fully controllable via Cerydra, and teammates’ mechanics sync perfectly with Mydei’s “health-for-damage” logic, turning all team resources into direct damage.

The Hypercarry Team follows: Sunday’s Turn Advance and Tribbie’s buffs enable fast output, but it’s limited by single-core numerical caps. Its rhythm is rigidly high-speed, and efficiency drops as resources go to team maintenance.

The Castorice Team is weakest: resources split for secondary DPS Castorice dilute Mydei’s output. Its rhythm depends on dual-DPS sync (prone to gaps), and Tribbie’s shared buffs minimize Mydei’s gains.

In short, the Cyrene Team is optimal for output, with clear advantages over the other two.

Conclusion

In conclusion, Cyrene outshines other supports for Mydei: her domain grants all-type RES PEN, synergistic attacks that add HP-scaled extra damage, and action speed boosts—all perfectly unlocking his "health-for-damage" potential.

These buffs not only deepen his damage by breaking enemy defenses but also stabilize his output rhythm by offsetting health loss. To fully maximize this unbeatable synergy and dominate Honkai: Star Rail, top up Honkai Star Rail via LDShop for secure, convenient transactions and exclusive perks!

Tsuki Yolo Experienced Game Editor

Hey, gamers! I'm Tuski Yolo. In the gaming universes of Genshin Impact, Honkai: Star Rail, and Wuthering Waves, I'm deeply familiar with every character's unique abilities and the ins-and-outs of gameplay. Whether it's optimizing team set-ups, mastering the art of farming for the best gear, or crafting the perfect character builds, I've got it all covered. With my guidance, you'll stride through the gaming world with unwavering confidence, transforming every in-game obstacle into a stepping stone to victory!