Cyrene's Best Team Comps Recommendation | Honkai: Star Rail 3.7

Good morning, Trailblazers!
Get ready: Honkai: Star Rail Version 3.7 is officially launching on November 5, 2025, marking the grand finale of the long-running Amphoreus saga! With this update, the long-awaited Cyrene finally joins the roster as a new Ice Remembrance support, and her potential is absolutely incredible.

Are you wondering who she synergizes best with? Or which team compositions can fully unleash her power? Don't worry! We've got you covered! In this guide, we'll walk you through 5 recommended teams for Cyrene, explaining how each works and why they're great. Let's dive right in and discover which one can bring out her full strength!

 

Cyrene + Castorice + Evernight +Hyacine

Cyrene	Castorice	Evernight	Hyacine
		Tribbie / Cipher / Trailblazer(Ice)

This team is widely considered by many theorycrafters as one of the strongest pairings with Cyrene. Its appeal lies in its tight synergy in buff propagation and energy cycling, enabling extremely high damage output.

• Complementary buff system: Evernight excels in supporting through her Memosprite interactions and grant of CRIT DMG buffs and team-wide bonuses, which Castorice — serving as main DPS — can fully leverage.
• HP–drain / healing synergy: Hyacine offers team-wide Max HP buffs and healing, and works especially well when there are HP consumption or recovery mechanics to trigger additional effects.
• High energy & trigger frequency: Cyrene is rumored to have a unique Ultimate that accelerates all allies' action bars and improve team energy flow, allowing more frequent Ultimate usage and tighter combos.
• Theoretical damage explosion: With ideal gear, speed tuning, and role coordination, this team can amplify each member's strength through cross-buffs, pushing Castorice's output to its ceiling. Many speculate this combination is the best way to maximize Cyrene's potential.

In short, this composition not only has strong parameter synergy but also strategic coherence and explosive damage potential, making it a top-tier team to pair with Cyrene.

 

Cyrene + Phainon + Cerydra + Dan Heng • Permansor Terrae

Cyrene	Phainon	Cerydra	Dan Heng • Permansor Terrae
		Sunday / Sparkle / Robin	Huohuo / Hyacine

This team builds on control and multi-action synergy, ideal for fights requiring both stability and sustained True DMG conversion:

• Extended action chains: Phainon's transformations and extra turns create longer attack sequences, giving Cyrene more proc opportunities per Zone.
• Elemental synergy and boosts: Cerydra's “military merit” effects grant conditional hits and amplify the team's total damage.
• Defensive reliability: Dan Heng provides steady shields and follow-ups, keeping long combo turns uninterrupted.
• Sustained True DMG output: Cyrene converts frequent ally actions into amplified True DMG, ensuring consistent pressure through prolonged fights.

 

Cyrene + Mydei + Tribbie + Hyacine

Cyrene	Mydei	Tribbie	Hyacine
		Ruan Mei / Sparkle / Trailblazer(Ice)	Lingsha / Huohuo / Luocha

This team centers on burst-assisted synergy, converting rapid action chains and amplified buffs into explosive True DMG output:

• High buff scaling: Tribbie grants strong stat boosts, turn acceleration, and “after-attack” Quantum hits, stacking multipliers for Cyrene's conversions.
• HP-based burst: Mydei's HP-charged swings and excess actions generate dense damage clusters, providing numerous proc triggers within short bursts.
• Sustain and endurance: Hyacine maintains team survivability so Mydei can safely consume HP and extend the attack flow.
• Amplified True DMG: Cyrene transforms every micro-hit and bonus tick from Tribbie and Mydei into amplified True DMG, creating powerful condensed damage windows.

 

Cyrene + Aglaea + Sunday + Hyacine

Cyrene	Aglaea	Sunday	Hyacine
		Tribbie / Robin / Trailblazer(Ice)	Huohuo / Dan Heng • Permansor Terrae / Lingsha

This team leans toward support/recovery + multi-utility, suited for fights requiring strong sustain, status management, and flexible responses:

• Broad auxiliary coverage: Aglaea and Sunday are often cast as support/control/status roles, providing acceleration, resistance debuffs, shielding, and other backup functions.
• Strong survivability & sustain: With Hyacine's healing and HP buffs, plus auxiliary control and protection, this team can endure prolonged engagements.
• Backup DPS flexibility: When the main DPS is constrained or strategy needs shift, support characters can sometimes chip in damage or utility benefit.
• Control + support synergy: In battles with many mechanics (e.g. debuffs, control phases), this team offers more tools to adapt and respond.

 

Cyrene + Anaxa + Tribbie + Hyacine

Cyrene	Anaxa	Tribbie	Hyacine
		Cerydra / Sunday / Trailblazer(Ice)	Dan Heng • Permansor Terrae / Lingsha / Aventurine

This team setup strikes a balance between supportive buffing and control, good for teams needing both damage and control flexibility:

• Powerful buffs + control blending: Tribbie's massive stat boosts, paired with Anaxa's potential control or interactive mechanics, allow combining output enhancement and control at key times.
• Steady damage support: Hyacine continues to supply HP buffs and sustain, helping the team maintain rhythm and resilience.
• Supplemental damage: Though lacking a pure DPS main, with good buff & control coordination, the total damage can still be solid.
• High adaptability: When fight conditions shift or mechanics intervene, this team has better leeway to pivot strategies rather than focusing solely on one burst window.

 

A little side note... I wonder how The Herta players are feeling this time? There’s practically no connection at all between The Herta and Cyrene in this update. After waiting an entire version for something to happen. Well, nothing did… Looks like our poor Herta mains really got left out in the cold this time!

Since this blog LDShop mainly introduces the five recommended Cyrene team compositions, we won't go into too much detail about her skills or build here.

If you'd like to check Cyrene's detailed skill and build guide, feel free to click the link — all the related information is available on LDShop!

 

Conclusion

That wraps up our look at Cyrene's top five team comps! Each lineup offers something unique, but the Castorice Team currently stands out as the most powerful and well-synergized choice.

For more Honkai: Star Rail updates, in-depth team analyses, and upcoming version details, make sure to follow LDShop! We'll always bring you the latest game information first!
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